Measuring microtubule thickness: an exercise in cooperativity.
نویسنده
چکیده
Doublecortin (DCX), a microtubule-associated protein, is essential for neuronal migration, although a clear mechanistic understanding of this requirement remains elusive. In this issue of Developmental Cell, Bechstedt and Brouhard (2012) report that DCX relies on cooperative binding and an affinity for growing microtubule ends to nucleate and stabilize 13-protofilament microtubules.
منابع مشابه
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ورودعنوان ژورنال:
- Developmental cell
دوره 23 1 شماره
صفحات -
تاریخ انتشار 2012